Ace Inhibitors

Forum for Addisons and diabetes related issues.

Ace Inhibitors

Postby clansing1 » Fri Feb 02, 2007 11:48 am

I wasdiagnosed with Primary Addison's Disease and Type I Diabetes 13 months ago.

I'm male and 34 years old and weight 165 lbs.

I've had really good AIC's over the past year with 6.3, 6.5, 5.2, and 5.7.

The med's I take are the following:

25 mg DHEA - GNC
Calcium
81 mg Aspirin
1 mg fludrocort in AM
.5 mg Prednisone at night
2.5 mg/5 mg/2.5 mg Cortef

I was wondering if Diabetes/Addison's patients should take an Ace Inhibitor to prevent Kidney disease?

I see that it increasings your potassium retention, which might be a problem with the Addison's. But I can always have my Potassium levels checked several weeks after I start taking the Ace Inhibitor

Thanks in advance.
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Postby NJ » Fri Feb 02, 2007 5:37 pm

The ACE inhibitor would be something an Addisonian should use with caution. I was given an Angiotensin II inhibitors for my BP and I was told it was used to help diabetics avoid kidney problems. It is a different class of drug than the ACE inhibitors.
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Postby SueM » Sat Feb 03, 2007 10:30 am

I've been on insulin for 42 years and have never used either a statin or and ACE inhib.
It is up to you to make an informed descion as to whether you take them.
I have the attitude if it ain't broke don't fix it.
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Postby gkardel » Wed Feb 07, 2007 11:04 pm

Good job with the A1c's. Probably not worth the risk of side effects that ACE inhibitors might bring. You're already doing a good job of managing the risk of kidney damage by managing your diabetes competently. I like Sue's approach - "if it ain't broke don't fix it".

Wow, you're on a low cortisol replacement dose. How do you feel on this dose? What's your dose timing?


Glenn
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Glen

Postby clansing1 » Thu Feb 08, 2007 9:34 am

Typo on the prednisone. It should be 5 mg at night. I take 5 mg of the cortef when I wake in the morning, 5 mg at lunch time, and 2.5 mg at about 4 PM.

I sometimes get a little tired during mid-morning, or feel anxiety building up, have trouble sleeping. Besides that I think I"m doing pretty good.

Thanks for the compliment on the A1C's. I work pretty hard at it. My professional backround is in civil/construction engineering which I think was a big help to figuring out these disease's. Engineerings love analyzing data, problem solving, critical thinkings, etc. ;-)

Chad
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Postby gkardel » Thu Feb 08, 2007 11:20 pm

Your regimen is similar to mine. I take 1mg prednisone at bedtime, 10mg cortef when I wake up, 2.5mg at lunch and 2.5 late afternoon. That's cool you're able to control your sugars so well with a higher cortisol replacement dose. You may want to try decreasing your pred dose and increasing your morning cortef dose to see if that helps with sleep, anxiety, morning tiredness.

Glenn
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Postby NJ » Sat Feb 10, 2007 5:21 pm

I take a combo of HC and prednisone, also. 20 mg. HC and 1.25 mg. prednisone and I take the prednisoe at 2:00 PM and if I need to increase for any reason I take extra HC not prednisone.
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Smaller Prednisone Dose

Postby clansing1 » Mon Feb 19, 2007 9:21 am

Glen, thanks for the info. I'm going to give the smaller prednisone dosage a try.
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Smaller Prednisone Dose

Postby clansing1 » Mon Feb 19, 2007 9:23 am

Glen, thanks for the info. I'm going to give the smaller prednisone dosage a try.
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